LANDMARK REVIEWS IN COPD

Pathogenesis & Pathology

1. Turatoa etal. Pathogenesis and Pathology of COPD. Respiration 2001;68:117–128.

2. MacIntyre etal. Acute Exacerbations and Respiratory Failure in Chronic Obstructive Pulmonary Disease. Proc Am Thorac Soc 2008;5:530–535, 2008.

Use of Steroids

1. Woods et al. Corticosteroids in the treatment of acute exacerbations of chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 2014;9:421-430.

2. Walters JAE et al. Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2014, Issue 9. Art. No.: CD001288.

Mechanical ventilation

1. Wakatsuki et al. Invasive mechanical ventilation in acute exacerbation of COPD: prognostic indicators to support clinical decision making. JICS 2012;13(3):238-243.

2. Nicholas S et al. Clinical concise review: Mechanical ventilation of patients with chronic obstructive pulmonary disease. Crit Care Med 2008 Vol. 36, No. 5.

Other medical treatments

1. Minor DS et al. β-Blockers and Chronic Obstructive Pulmonary Disease: Inappropriate Avoidance? J Clin Hypertens 2013;15:925–930.

Role of NIV

1. Hess et al. Heliox and Noninvasive Positive-Pressure Ventilation: A Role for Heliox in Exacerbations of Chronic Obstructive Pulmonary Disease? Respir Care 2006;51(6):640–650.

2. Lightowler JV et al. Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis. BMJ. 2003 Jan 25;326(7382):185.

3. Ram FS et al. Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2004;(3):CD004104.

LANDMARK STUDIES IN COPD

Use of Steroids

1. Alía I et al. Efficacy of Corticosteroid Therapy in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease Receiving Ventilatory Support. Arch Intern Med. 2011;171(21):1939-1946.

2. Lindenauer PK. Association of Corticosteroid Dose and Route of Administration With Risk of Treatment Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease. JAMA. 2010;303(23):2359-2367.

3. Rothberg MB. Antibiotic Therapy and Treatment Failure in Patients Hospitalized for Acute Exacerbations of Chronic Obstructive Pulmonary Disease. JAMA. 2010;303(20):2035-2042.

4. Leuppi JD. Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseThe REDUCE Randomized Clinical Trial. JAMA. 2013;309(21):2223-2231.

Role of NIV

1. Brochard L et al. Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease. N Engl J Med 1995; 333:817-822.

2. Kumar A et al. Factors leading to poor outcome of noninvasive positive pressure ventilation in acute exacerbation of chronic obstructive pulmonary disease. Journal of Acute Disease (2015)44-47.

3. Khilani GC et al, Non-invasive ventilation for acute exacerbation of COPD with very high PaCO2: A randomized controlled trial. Lung India. 2010 Jul-Sep; 27(3): 125–130.

COPD/ASTHMA overlapping syndrome

1. Jeffrey M. Review Article: The Asthma–COPD Overlap Syndrome. N   Engl J Med 2015;373:1241-9.

Compiled by

Dr Sananta K Dash & Biswabikash Mohanty