ARDS LANDMARK PUBLICATIONS

Definition

 

  1. Bernard. The American European consensus conference on ARDS: definitions mechanisms, relevant outcomes and clinical trial coordination, Am J Respir Crit Care Med 1994; 149:818–24.
  2. Murray. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988;138(3):720-3.
  3. The ARDS Definition Task Force. Acute Respiratory Distress Syndrome. The Berlin Definition. JAMA 2012;307(23):2526-2533.

 

Ventilatory strategies & PEEP

 

  1.  The Acute Respiratory Distress Syndrome Network. Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome. N Engl J Med 2000; 342:1301-1308.
  2. Villar J. A high positive end-expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome: a randomized, controlled trial (AIRES Study). Crit Care Med 2006; 34:1311-1318.
  3. The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome. N Engl J Med 2004;351:327-36.
  4. Meade MO. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: A randomized controlled trial. JAMA 2008; 299:637-645.

 

Recruitment strategies & effect

 

  1. Gattinoni. Lung Recruitment in Patients with the Acute Respiratory Distress Syndrome. N Engl J Med 2006;354:1775-86.
  2. Brower. Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med 2003;31:2592-2597.

 

Strategies for refractory hypoxia (HFOV, ECMO, Prone ventilation

 

  1. Ferguson. High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome (OSCILLATE). New Engl J Med 2013;epublished January 22rd.
  2. Young. High-Frequency Oscillation for Acute Respiratory Distress Syndrome (OSCAR). New Engl J Med 2013;epublished January 22nd.
  3. Peek. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet 2009; 374: 1351-63.
  4. Taccone. Prone Positioning in Patients With Moderate and Severe Acute Respiratory Distress Syndrome. A Randomized Controlled Trial. JAMA. 2009;302(18):1977-1984.
  5. Mancebo. A multicentre trial of prolonged prone ventilation in severe acute respiratory distress syndrome.  Am J Respir Crit Care Med. 2006;173:-1233-1239.
  6. Guérin. Prone Positioning in Severe Acute Respiratory Distress Syndrome (PROSEVA). New Engl J Med 2013;368:2159-2168.

 

Fluid therapy in ARDS

 

  1. Wiedemann. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 2006; 354:2564-75.

 

Monitoring in ARDS

 

  1. Wheeler. Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. N Engl J Med. 2006; 354:2213-24.

 

Feeding & nutrition in ARDS

 

  1. The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Initial Trophic vs Full Enteral Feeding in Patients With Acute Lung Injury: The EDEN Randomized Trial. JAMA 2012;epublished February 5th .

  2. Rice. Enteral Omega-3 Fatty Acid, γ-Linolenic Acid, and Antioxidant Supplementation in Acute Lung Injury. JAMA 2011;306(14):1574-1581.

  3. Stapleton. A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury. Crit Care Med. 2011;39(7):1655-62.

 

Pharmacological therapy in ARDS (NMBD, Steroid, Beta agonist & nitric oxide)

 

  1. Papazian. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107-1116.  

  2. Meduri. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest 2007; 131:954-63.

  3. Steinberg. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006; 354:1671-84. 

  4. Perkins. The Beta-Agonist Lung Injury Trial (BALTI): A Randomized Placebo-controlled Clinical Trial.  Am J Respir Crit Care Med 2006;173:281–287.

  5. Adhikari. Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ 2007; 334 : 779.

 

 

                                                                                                                                                                                                                    Compiled by - Dr Biswabikash Mohanty

 

 

 

 

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